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CHAPTERS: Chapter 1-5
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DEPRESSION AND ANXIETY PSYCHOLOGICAL FACTORS INFLUENCING THE WELL-BEING OF PEOPLE LIVING WITH SICKLE CELL ANAEMIA IN EZINIHITTE LOCAL GOVERNMENT AREA,LMO-STATE
Abstract
This study examined the psychological factors, particularly depression and anxiety, that influence the well-being of individuals living with Sickle Cell Anaemia (SCA) in Ezinihitte Local Government Area, Imo State. The primary objective was to explore the prevalence of depression and anxiety among individuals with SCA, their impact on physical health and quality of life, and the role of social and environmental factors such as family support and access to healthcare in shaping mental health outcomes. Given the chronic and debilitating nature of SCA, understanding the psychological impact is crucial in improving the overall care and quality of life for affected individuals. A cross-sectional survey research design was employed, and a structured questionnaire was used to gather data from a sample of 133 respondents. The data was analyzed using SPSS version 27, employing descriptive statistics to provide a clear picture of the demographic characteristics of the respondents. The hypotheses were tested using a one-sample t-test, allowing the study to evaluate the significance of the relationship between depression and physical health, anxiety and quality of life, and the influence of social and environmental factors on mental health. The findings revealed that depression and anxiety were prevalent among individuals living with SCA. A significant proportion of respondents reported experiencing feelings of sadness, hopelessness, and anxiety, which they believed negatively impacted their ability to manage physical pain and affected their overall daily activities and quality of life. These results support previous studies that have highlighted the comorbidity of mental health disorders such as depression and anxiety in individuals with chronic illnesses like SCA. Furthermore, the study found that social and environmental factors, including the availability of family support and access to healthcare services, played a critical role in shaping the mental health and well-being of individuals with SCA. A lack of social support was perceived to contribute significantly to emotional struggles, and limited access to healthcare services worsened mental health conditions. These findings emphasize the need for a holistic approach to healthcare for individuals with SCA that addresses both physical and psychological needs. Overall, the study highlighted the importance of considering mental health as an integral part of SCA management. It concluded that improving healthcare services and enhancing social support systems could significantly improve the mental well-being of individuals living with SCA. The findings call for further research to better understand these psychological challenges and to design targeted interventions aimed at improving the quality of life for individuals with SCA.
CHAPTER ONE
INTRODUCTION
1.1 Background to the Study
Sickle Cell Anaemia (SCA) is a hereditary blood disorder characterized by abnormal hemoglobin, which causes red blood cells to assume a rigid, sickle-like shape. This abnormality significantly impacts the oxygen-carrying capacity of the blood, resulting in a wide range of complications such as severe pain, anemia, and organ damage (Bhatia & Walters, 2020). The sickling of the red blood cells obstructs blood flow and causes a blockage in the small blood vessels, leading to tissue damage and painful episodes known as “sickle cell crises.” Sickle cell crises can occur without warning and may last for hours or days, significantly affecting the quality of life for individuals living with the condition (Weatherall & Clegg, 2021).
In Nigeria, SCA is a major public health concern, with a high prevalence, especially in regions such as the southeastern part of the country, including Imo State. It is estimated that one in every four Nigerians carries the sickle cell trait, and the country has one of the highest rates of SCA globally (Anie et al., 2021). The burden of the disease is enormous, as individuals with SCA are faced with not only the physical pain and complications but also the socio-economic costs of ongoing medical treatments, hospital visits, and lost productivity (Ohaeri et al., 2021). The high prevalence and severity of SCA in Nigeria have prompted public health initiatives, yet significant gaps in medical care and psychological support remain.
Living with SCA involves numerous physical and psychological challenges. The physical toll of the disease is evident in frequent hospitalizations, blood transfusions, and the long-term management of organ damage. However, the psychological burden of the disease is just as profound. Individuals with SCA often face depression and anxiety, which can be triggered by the unpredictable nature of the disease, the severity of the symptoms, and the limitations imposed on daily activities (Riddington & Owusu-Ofori, 2022). Depression is characterized by persistent feelings of sadness, hopelessness, and a lack of interest in activities that were once enjoyable. Anxiety, on the other hand, involves a constant state of worry or fear about the future and the progression of the disease. These psychological conditions are common among individuals with chronic illnesses, including SCA, and they can compound the challenges associated with managing the physical aspects of the disorder (Thompson et al., 2020).
The psychological factors of depression and anxiety have been shown to reduce the quality of life and affect the functional abilities of individuals with chronic conditions (Gil et al., 2023). Depression, for example, may lead to reduced motivation to follow treatment protocols, which in turn can lead to worsening physical health and more frequent crises. Anxiety can create a heightened state of vigilance, with individuals constantly worrying about potential health complications or future crises. Both conditions increase the risk of complications and make disease management more challenging. Individuals living with SCA often struggle to cope with the dual burden of managing both their physical symptoms and the emotional toll that the disease takes on their mental health (Moos & Schaefer, 2020).
In Ezinihitte Local Government Area, Imo State, the psychological well-being of individuals living with SCA has been largely underexplored. While there have been studies conducted on the physical aspects of SCA care, little attention has been paid to the psychological experiences of individuals with the disease in this specific region (Uwakwe et al., 2023). This gap in research is particularly concerning given the socio-economic context of rural and semi-urban communities in Imo State, where access to healthcare services may be limited, and the mental health needs of individuals with chronic conditions may be overlooked. Family and community support, which plays a critical role in the management of chronic illness, may also be limited in these areas, further exacerbating the psychological burden faced by individuals with SCA (Omonzejele, 2022).
Understanding how depression and anxiety affect the well-being of individuals with SCA in Ezinihitte is crucial for developing targeted interventions that address both the physical and psychological aspects of the disease. Without addressing the mental health needs of these individuals, efforts to improve their physical health and overall quality of life may fall short. Research into the prevalence and impact of depression and anxiety on SCA patients in Ezinihitte will provide valuable insights into the challenges these individuals face and inform the development of integrated care models that include both medical treatment and psychological support (Thompson et al., 2021).
Furthermore, examining the relationship between depression, anxiety, and the well-being of people with SCA will also shed light on the broader social and environmental factors that contribute to their mental health. Family support, community resources, and access to healthcare services all play an important role in the psychological well-being of individuals with chronic illnesses, including SCA. The findings of this study could also influence public health policies aimed at improving mental health services for people living with SCA, particularly in rural and underserved areas like Ezinihitte (Nzewi, 2021).
This research aims to fill the gap in knowledge regarding the psychological impact of SCA in Ezinihitte Local Government Area, Imo State. By investigating the prevalence of depression and anxiety among individuals with SCA and exploring the ways in which these psychological factors influence their overall well-being, this study hopes to contribute to the development of more comprehensive care approaches for people living with the disease. Addressing the mental health needs of individuals with SCA is not only crucial for their well-being but is also essential for enhancing their physical health outcomes and reducing the burden of the disease on both the individuals and the healthcare system (Anie et al., 2010).
By shedding light on the complex relationship between the physical and psychological aspects of living with SCA, this study will provide a foundation for future research and interventions aimed at improving the lives of individuals with SCA in Nigeria. The ultimate goal is to ensure that individuals with this chronic condition are not only receiving adequate medical care but are also supported psychologically, which will enable them to lead fuller, more productive lives despite the challenges posed by SCA.
1.2 Statement of the Problem
Sickle Cell Anaemia (SCA) remains a significant public health challenge in many parts of the world, especially in regions such as sub-Saharan Africa, where its prevalence is notably high (Weatherall & Clegg, 2021). While extensive research has been conducted on the physical complications of SCA, there remains a substantial gap in understanding the psychological factors that influence the well-being of individuals living with the condition, particularly in Nigeria and other African countries. Specifically, there is limited research focused on the impact of depression and anxiety among SCA patients in rural and less-studied localities, such as Ezinihitte Local Government Area in Imo State, Nigeria.
Previous studies have acknowledged the psychological toll that chronic illnesses like SCA can have on patients (Uwakwe, Kofie, & Shokumbi, 2023). However, most of these studies are either focused on specific urban centers or have failed to delve deeply into the unique psychological challenges faced by individuals in rural areas. For example, research by Anie et al. (2021) conducted a cross-cultural study on psychosocial aspects of SCA in both the UK and Nigeria, but it did not specifically address the rural Nigerian experience. This leaves a gap in understanding how rural patients’ coping mechanisms, emotional distress, and social support networks may differ from those of urban dwellers.
Another significant gap in the literature is the limited focus on how depression and anxiety interact with other health complications specific to SCA, such as the recurrent pain crises and the long-term effects of organ damage (Riddington & Owusu-Ofori, 2022). While studies like those by Ohaeri et al. (2021) have explored the psychosocial problems faced by SCA patients, they often concentrate on general coping mechanisms without specifically linking mental health disorders to the chronic pain and hospitalizations that are intrinsic to the disease. More research is needed to explore how the interplay between physical and psychological factors exacerbates the overall burden of the disease, particularly in regions with limited healthcare resources.
Additionally, existing studies have predominantly focused on the impact of SCA on children and adolescents, with limited research addressing the psychological needs of adults living with the condition. According to Moos and Schaefer (2020), chronic physical illness often requires coping strategies that evolve over time. However, there is a lack of longitudinal studies that examine how depression and anxiety develop and change over the lifespan of individuals living with SCA. This leaves an important gap in understanding the progression of mental health issues within the SCA community.
Finally, the cultural context in which individuals with SCA live remains underexplored. Nzewi (2021) raised the issue of cultural beliefs, such as the notion of the “malevolent ogbanje,” which could influence how individuals with SCA are perceived and how they cope with their condition. The role of cultural perceptions in the psychological well-being of SCA patients in specific Nigerian communities, such as those in Ezinihitte Local Government Area, remains an area ripe for exploration.
Thus, there is a pressing need for research that fills these gaps, particularly in terms of understanding the psychological factors, including depression and anxiety, that affect people living with SCA in rural Nigerian communities. By addressing these gaps, future studies can inform more effective, culturally sensitive interventions and support systems that improve the mental and physical health of individuals affected by SCA.
1.3 Objectives of the Study
The main objective of this study is to examine the psychological factors, specifically depression and anxiety, influencing the well-being of individuals living with Sickle Cell Anaemia in Ezinihitte Local Government Area, Imo State. The specific objectives are as follows:
- To investigate the prevalence of depression and anxiety among individuals living with SCA in Ezinihitte.
- To assess the impact of depression and anxiety on the physical health and quality of life of people with SCA in this region.
- To explore the social and environmental factors that contribute to the psychological well-being of individuals living with SCA.
- To recommend strategies for improving the psychological support and overall well-being of SCA patients in Ezinihitte Local Government Area.
1.4 Research Questions
The study will be guided by the following research questions:
- What is the prevalence of depression and anxiety among individuals living with Sickle Cell Anaemia in Ezinihitte Local Government Area, Imo State?
- How do depression and anxiety affect the physical health and quality of life of individuals with SCA in Ezinihitte?
- What are the social and environmental factors that influence the mental health and well-being of individuals with SCA in this region?
1.5 Research Hypotheses
The following hypotheses will guide the study:
- There is no significant relationship between depression and the physical health of individuals living with Sickle Cell Anaemia in Ezinihitte Local Government Area.
- Anxiety levels among people with SCA are not significantly correlated with their overall quality of life.
- Social and environmental factors, such as family support and access to healthcare, do not significantly influence the psychological well-being of individuals living with SCA.
1.6 Significance of the Study
This study is significant for several reasons. First, it will contribute to the growing body of knowledge on the psychological factors that affect individuals living with chronic illnesses, particularly Sickle Cell Anaemia. By examining the mental health challenges faced by SCA patients in Ezinihitte Local Government Area, the study will provide valuable insights into the extent of depression and anxiety in this population.
Second, the findings of this study will help in the development of targeted interventions to improve the psychological well-being of individuals with SCA. Addressing the mental health needs of these individuals is crucial for enhancing their overall quality of life and ensuring better disease management. The study will also inform healthcare providers and policymakers about the importance of integrating mental health care into the treatment and support systems for people with SCA.
Third, the research will help to raise awareness of the mental health challenges faced by individuals with SCA in the local community and advocate for better psychological support services for these individuals.
1.7 Scope of the Study
This study will focus on individuals living with Sickle Cell Anaemia in Ezinihitte Local Government Area, Imo State. The research will explore the prevalence of depression and anxiety in this population and how these conditions impact their well-being. The scope of the study will be limited to adult individuals (18 years and above) diagnosed with SCA in the area. The study will not include individuals with other chronic illnesses or children living with SCA, as the focus is specifically on adults and their psychological health.
The study will also examine the social and environmental factors influencing the mental health of people with SCA, such as family support, access to healthcare, and community attitudes toward SCA. However, the study will not explore other aspects of SCA management, such as medical treatments and interventions.
1.8 Operational Definition of Terms
- Sickle Cell Anaemia (SCA): A genetic blood disorder characterized by the production of abnormal hemoglobin, leading to the distortion of red blood cells into a sickle shape, causing various health complications such as pain, anemia, and organ damage.
- Depression: A psychological condition marked by persistent feelings of sadness, hopelessness, and a lack of interest in daily activities, often leading to impaired functioning and a reduced quality of life.
- Anxiety: A psychological condition characterized by excessive worry, fear, or nervousness about potential future events, often resulting in physical symptoms such as restlessness, increased heart rate, and difficulty concentrating.
- Well-being: A multidimensional concept that includes physical, psychological, and social aspects of an individual’s life. In this study, it refers to the overall quality of life and mental health of individuals living with SCA.
- Prevalence: The proportion of individuals within a specific population who exhibit a particular characteristic or condition, in this case, depression or anxiety, at a given time.
- Psychological Factors: Mental or emotional aspects that influence an individual’s thoughts, feelings, and behaviors. In this study, depression and anxiety are the primary psychological factors being examined.
- Social Support: The emotional, informational, and practical assistance provided by family, friends, and the community, which can play a significant role in managing chronic illnesses such as SCA.
- Environmental Factors: External influences on an individual’s mental health and well-being, including access to healthcare, socioeconomic status, and community attitudes toward SCA.