ABSTRACT Cassytha filiformis, a leafless and perennial vine with small scales as a replacement of the leavesis currently being used in the treatment of various disease conditions including jaundice without standardization.Microscopical evaluation, chromatographic analysis (TLC, HPLC, LC-MS/MS), spectroscopic analyses (NMR, FTIR, MS) and hepathoprotective studies were carried out with the view to scientifically verify the […]
SCHOOL PROJECT TOPICS BY DEPARTMENT: Pharmacy project topics and materials
Pharmacy project topics and materials
PHARMACOECONOMIC ANALYSIS OF HIV/AIDS MANAGEMENT
ABSTRACT The HIV/AIDS pandemic has resulted in mortality surge and life expectancy drop throughout the world. Developing countries are mostly affected due to their limited health care system and resources to handle the increasing costs of management of HIV/AIDS and associated opportunistic infections. The objective of this study is to estimate direct and indirect costs […]
ANTIMICROBIAL ACTIVITY OF METHANOL EXTRACT AND FRACTIONS OF MORINGA OLEIFERA LAM. ROOT BARK ON CLINICAL ISOLATES OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS
ABSTRACT Development of antimicrobial resistance by bacteria is now a world wide health issue, as infection is one of the leading causes of death in the world today. This fact is also as a result of the emergence of multiple antibiotic resistant bacteria known as methicillin resistant Staphylococcus aureus (MRSA) with potential of cross resistance […]
PHYTOCHEMICAL STUDIES AND EVALUATION OF THE ANTITRYPANOSOMAL ACTIVITY OF VITEX SIMPLICIFOLIA OLIV. (VERBENACEAE) LEAF
ABSTRACT Background Trypanosomiasis, a disease of major importance in human and animals has continued to threaten human health and economic development. Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense as the etiological agents of trypanosomiasis affect millions of people in sub-saharan Africa and are responsible for the death of about half a million patients per year. […]
DEVELOPMENT OF LIPID-BASED MICRO SUSPENSIONS FOR OPHTHALMIC DELIVERY OF GENTAAMICIN
ABSTRACT The bioavailability of drugs from conventional eye drops is generally low. Many studies have demonstrated that new and more complex ophthalmic drug forms exhibit advantage over traditional ones and are able to increase the bioavailability of the active substance by, among others, reducing the susceptibility of drug forms to defense mechanisms of the human […]
ANTIHYPERLIPIDEMIC AND ANTIOXIDANT EFFECTS OF PHASEOLUS VULGARIS LINN IN WISTAR RATS
ABSTRACT In this study, the antihyperlipidemic and antioxidants activities of the extract and fractions of Phaseolus vulgaris L. were evaluated. The crude extract (PVE) of dried pulverized plant material was obtained by maceration in methylene chloride/methanol (1:1) while the solvent fractions were obtained by successive solvent-solvent partition in separating funnel between the crude extract suspended […]
WOUND HEALING AND ANTI-INFLAMMATORY ACTIVITIES OF CEIBA PENTENDRA (L.) GAERTN IN WISTAR RATS
ABSTRACT Wound healing is a natural process that enables tissue repair after an injury while inflammation is a pathophysiological response of living tissue to injuries. To shorten the duration and minimize associated complications of wounds, wounds are treated with medications. Currently there is a growing interest in the use of traditional wound dressing agents such […]
PHARMACOLOGICAL ASSESSMENT OF Lupinus arboreus Sims (FABACEAE) METHANOL EXTRACT AND THREE ACTIVE CONSTITUENTS FOR ANTINOCICEPTIVE AND ANTI-INFLAMMATORY EFFECTS
ABSTRACT The methanol extract and chemical constituents of Lupinus arboreus leaf were investigated for antinociceptive and anti-inflammatory activities. The study was by experimental design. the extract was partitioned to yield hexane, ethylacetate, and methanol fractions. Phytochemical tests were done on the extract and fractions. Acute toxicity test (LD50) was carried out on crude methanol leaf […]
ECOFRIENDLY SYNTHESIS OF METFORMIN LOADED SILVER NANOPARTICLES USING NATURAL POLYMERS AND SYNTHESISED STARCH AS STABILIZING AGENTS
ABSTRACT Metformin loaded silver nanoparticles were synthesized using ecofriendly method with extract of Azadiractha indica as reducing agent and two natural polymers; guar gum and xanthan gum, Sodium alginate, and a semi- synthetic polymer (AMS) as stabilizing agents. Twelve batches of nanoparticles were synthesized. Nanocomposites synthesized from AMS were designated as AMS 1% NANOmet, AMS3% […]
ANTIHYPERLIPIDEMIC AND ANTIOXIDANT EFFECTS OF PHASEOLUS VULGARIS
ABSTRACT In this study, the antihyperlipidemic and antioxidants activities of the extract and fractions of Phaseolus vulgaris L. were evaluated. The crude extract (PVE) of dried pulverized plant material was obtained by maceration in methylene chloride/methanol (1:1) while the solvent fractions were obtained by successive solvent-solvent partition in separating funnel between the crude extract suspended […]
THE CAUSES AND EFFECTS OF CHOLERA AMONG CHILDREN
ABSTRACT This research work was designed to examine and analyze the causes and effects of cholera during raining season in Benin City. Seven (7) research questions were formulated and questionnaires were administered to one hundred and fifty (150) respondents in order to gather data for the research. Results showed that poor environment sanitation leads to […]
INVESTIGATION OF THE SOCIAL AND ECONOMIC IMPACT AND CONSEQUENCES OF CHRONIC DISEASES ON LOW INCOME EARNING FAMILY
Chapter one Introduction 1.1 Background of the Study It is well documented that in public health terms chronic diseases have come to “matter” in developing countries, where they impose a sizeable and growing disease burden (WHO 2001). The Global Burden of Disease (GBD) project estimates that as of 2002, chronic or non-communicable conditions accounted for […]
DETERMINING THE RECREATIONAL HEALTH PRACTICES BY PREGNANT WOMEN IN SELECTED ANTENATAL CLINICS
INTRODUCTION Pregnancy is the development of one or more offsprings, known as an embryo or fetus, in a woman’s uterus. This spans a period from fertilization of the female sex cell by the male sex cell to the birth of the offspring. This period is also called gestation period. The cells undergo rapid division and […]
REVIEWING THE NUTRITIONAL AND PHARMACOLOGICAL IMPORTANCE IN COMMON VEGETABLES IN NIGERIA
INTRODUCTION Vegetables are those herbaceous plants whose part or parts are eating as supporting food or can serve as the main foods. They may be aromatic, bitter or tasteless (Edema, 1987). Leafy vegetables also called potherbs, green vegetables or salad green are plants leaves eaten as vegetables sometimes they are accompanied by tender petioles and […]
THE USE OF QUALITY CONTROL PARAMETERS IN THE EVALUATION OF VEGETABLE CRUDE DRUGS
CHAPTER ONE INTRODUCTION BACKGROUND OF THE STUDY The universal role of plants in the treatment of disease is exemplified by their employment in all the major systems of medicine irrespective of the underlying philosophical premise. How and when such medicinal plants were first used ,is, in many cases, lost in pre-history, indeed animals other than […]
ASSESSMENT ON ANALYSIS OF WATER POLLUTION BY PHISPHATE
CHAPTER ONE INTRODUCTION BACKGROUND OF THE STUDY The universal role of plants in the treatment of disease is exemplified by their employment in all the major systems of medicine irrespective of the underlying philosophical premise. How and when such medicinal plants were first used ,is, in many cases, lost in pre-history, indeed animals other than […]
PHYTOCHEMICAL AND ANTIMICROBIAL ANALYSIS OF MYSTETOE LEAVES
ABSTRACT The sample of Mistletoe leaves was collected from an orange tree at Ururo in Umunze Anambra State. The leaves was extracted by using some solvent like ethanolic solvent, aqueous solvent n-hexane solvent and ethyl acetate solvent. The extracts was further analyzed which helps in determining the presence of phytochemical compounds in the Mistletoe plant […]
AVAILABILITY AND STORAGE OF VACCINES IN COMMUNITY PHARMACIES
CHAPTER ONE INTRODUCTION 1.0 Background of the Study Immunization is the process by which an individual’s immune system becomes fortified against an agent (known as the immunogen). When this system is exposed to molecules that are foreign to the body, called non-self, it will orchestrate an immune response, and it will also develop the ability […]
PROFILE OF ANTIBIOTIC USE AT THE HEALTH CENTRE
Abstract The indiscriminate use of antibiotics has become a global problem with implications for effective therapy of infections and dose resistance. The objective of this study is to determine the profile of antibiotic use at the health centre of Delta State University, Abraka. This study was a retrospective study of 592 patient prescriptions from January […]
ESTIMATION OF THE EFFECT OF CISAMPELOUS OWANRENSIS BENZENE FRACTION ON GLUCOSE ABSORPTION ACROSS THE INTESTINAL EPITHELIUM OF WISTER RATS ON ALOXAN INDUCED DIABETES
ABSTRACT Diabetes is a global public health crisis that threatens the economies of all nations, particularly developing countries. It is generally characterized by hyperglycaemia and hyperlipidaemia culminating in severe morbidities. This study aimed to assess the effects of Cissampelos owanrensis on glucose absorption in alloxan-induced diabetic male Wistar rats. Twenty (20) adult. Wistar rats were […]
THE EFFECT OF Cisampelous Owarensis BENZENE FRACTION ON GLUCOSE ABSORPTION ACROSS THE INTESTINAL EPITHELIUM OF WISTER RATS ON ALOXAN INDUCED DIABETES
ABSTRACT Diabetes is a global public health crisis that threatens the economies of all nations, particularly developing countries. It is generally characterized by hyperglycaemia and hyperlipidaemia culminating in severe morbidities. This study aimed to assess the effects of Cissampelos owanrensis on glucose absorption in alloxan-induced diabetic male Wistar rats. Twenty (20) adult Wistar rats were divided into […]
RECYCLING WASTE POLYETHYLENE MATERIALS TO USEFUL PRODUCTS VIA PYROLYSIS
Chapter one Introduction 1.1 Background of study Recycling is a process of changing waste materials into new products to prevent waste of potentially useful materials, reduce the consumption of fresh raw materials, energy usage, water and air pollution (from incineration), and lower greenhouse gas emissions as compared to plastic production. Recycling is a key component […]
INVESTIGATING THE PRESENCE OF STAPHYLOCOCCUS AUREUS AND ESCHERICHIA COLI IN DAIRY PRODUCTS
CHAPTER ONE INTRODUCTION 1.1 BACKGROUND OF THE STUDY Dairy products are various products derived from cow’s milk or that of other female mammals such as goat, sheep, yaks, horses, camel. Dairy products include yoghurt, nono (fermented cow’s milk, madara (unfermented cow’s milk, cheese, whey, condensed and evaporated milk.) (cultureforhealth, 2015). Yoghurt, nono, Madara has become […]
WORKING CAPITAL MANAGEMENT AND PROFITABILITY OF LISTED PHARMACEUTICAL FIRMS IN NIGERIA
ABSTRACT Working capital managemt involves the management of the most liquid resources of the firm which includes cash and cash equivalents, inventories, trade debtors and other receivables. Most firms do not ensure optimal level of working capital and this has been a major obstacle to their overall profitabilty. The study examined the impact of working […]
DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF RISPERIDONE IN PURE AND TABLET DOSAGE FORMS
ABSTRACT Two simple, sensitive, accurate and extraction-free spectrophotometric methods were developed and described for the determination of risperidone in pure and in tablet dosage forms. The methods are based on the formation of ion-pair complex between risperidone and the dyes bromocresol green in method A and thymol blue in method B at room temperature to […]
PHARMACOECONOMIC ANALYSIS OF HIV/AIDS MANAGEMENT PHARMACY
ABSTRACT The HIV/AIDS pandemic has resulted in mortality surge and life expectancy drop throughout the world. Developing countries are mostly affected due to their limited health care system and resources to handle the increasing costs of management of HIV/AIDS and associated opportunistic infections. The objective of this study is to estimate direct and indirect costs […]
ISOLATION OF MICROORGANISM ASSOCIATED WITH DETERIORATION OF BANANAS FRUITS
CHAPTER ONE INTRODUCTION Banana is a long curved fruit which grows in clusters and has soft pulpy flesh and yellow skin when ripe.There are about 1000 varieties of bananas in the world. Banana is an edible fruit botanically a berry, produced by several kinds of large herbaceous flowering plants in the genus Musa. In some […]
ROLE OF PHARMACOKINETICS AND METABOLISM IN DRUG DESIGN
ROLE OF PHARMACOKINETICS AND METABOLISM IN DRUG DESIGN ABSTRACT Drug discovery and development involve the utilization of in vitro and in vivo experimental models. Different models, ranging from test tube experiments to cell cultures, animals, healthy human subjects, and even small numbers of patients that are involved in clinical trials, are used at different stages […]
BACTERIA RESPONSIBLE FOR UPPER URINARY TRACT INFECTION
BACTERIA RESPONSIBLE FOR UPPER URINARY TRACT INFECTION IN 5 CHILDREN ATTENDING GOVERNMENT SECONDARY SCHOOL MAKARFI CHAPTER ONE INTRODUCTION 1.1. Introduction In biology/ecology, parasitism is a non-mutual symbiotic relationship between species, where one species, the parasite, benefits at the expense of the other, the host. Traditionally parasite (in biological usage) referred primarily to organisms visible to […]
AUTOMATION IN INVENTORY MANAGEMENT IN THE PHARMACEUTICAL UNIT OF THE HOSPITAL
CHAPTER ONE INTRODUCTION 1.0 Introduction A pharmaceutical inventory management system is a computerized system that facilitates the inventory management of pharmaceutical products. An automated inventory management system can be categorized as an aspect of computer field of management information system (MIS) and it cannot exist without a proper database management which remains one of the […]